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Is The Popular Pain Medication Tramadol Always Safe? Tramadol is a popular prescription pain medication that helps patients in the treatment of moderate to severe pain. It alters and modifies the transmission of pain signals to the brain. As a result, a user experiences less intense pain while taking tramadol. Tramadol works in similar manner as other anti-depressants but it’s more effective. The drug increases the levels of serotonin and norepinephrine in human body. The drug comes with a number [...]